Influence of low protein diets on gene expression of digestive enzymes and hormone secretion in the gastrointestinal tract of young weaned piglets     

Zhi-mei Tian  Xian-yong Ma  Xue-fen Yang  Qiu-li Fan  Yun-xia Xiong  Yue-qin Qiu  Li Wang  Xiao-lu Wen  Zong-yong Jiang 《Journal of Zhejiang University. Science. B》2016,17(10):742-751

To investigate dietary protein level effects on digestive mechanisms, weaned piglets were fed for 45 d with diets containing 20%, 17%, or 14% crude protein (CP) supplemented to meet requirements for essential amino acids. This article describes the influence of dietary protein on gastrointestinal hormones and expression of an array of digestive enzymes in the gastrointestinal tract and pancreas. Results indicated that there were no significant differences in expression of enzymes involved in carbohydrate digestion, except for maltase in the duodenum. In the jejunum, amylase expression in pigs fed 20% CP was much higher than that in pigs fed other diets (P<0.05) and maltase expression in those fed 17% CP was higher than that in other treatments (P<0.05). Although there were no remarkable differences in expression of aminopeptidase in the small intestine or carboxypeptidase in the pancreas (P>0.05), there was a trend towards higher expression of various proteases in pigs fed 17% CP. The duodenal expression of enteropeptidase in diets with 14% and 17% CP was significantly higher than that with 20% CP (P<0.05), but treatment differences did not existed in jejunum (P>0.05). The expression of GPR93 as a nutrient-responsive G protein-coupled receptor in 14% and 17% CP diets was significantly higher than that in 20% CP diet in the small intestine (P<0.05). The expressions of genes for pancreatic enzymes, lipase and elastase, were significantly higher in pigs fed diets with low CP, while similar trends occurred for carboxypeptidase, chymotrypsin and amylase. Conversely, the gastric expressions of pepsinogen A and progastricsin were lower with the 17% CP diet. Differences between treatments were found in the gastric antral contents of cholecystokinin and somatostatin: both increased in pigs fed 17% CP, accompanied by decreased content of motilin, which was also seen in plasma concentrations. These patterns were not reflected in duodenal contents. In general, 17% dietary CP was beneficial to the digestion of nutrient substance in the gastrointestinal tract.  相似文献   

英文歌曲在多媒体大班英语教学中的应用   总被引：1，自引：0，他引：1  

马俊波 《沙洋师范高等专科学校学报》2005,6(4):82-84

本文在借鉴前人经验的基础上，联系教学实例介绍了英文歌曲在多媒体大班英语教学中的作用扣在多媒体大班英语教学中应用英文歌曲的选材原则、基本步骤及注意事项，以期对改善多媒体大班英语教学的效果有一定的参考作用。  相似文献   

树立企业教育与培训的新理念     

张桂利  缑英俊  马勇 《现代企业教育》2003,(6):34-34

企业传统教育与培训的不足 (一)观念滞后 重视不足 受传统观念的束缚及眼前经济利益的影响,当前不少企业存在着思想偏见。有些企业的领导把企业教育与培训看作是"多余的婴儿",可有可无。只要企业盈利,理论上是否搞清楚并不重视。为此在工作中出现了"说起来重要、干起事次要、忙起来不要"的工作态度。从而形成了"一看、二慢、三通过"的错误理念,与市场经济的要求格格不入。  相似文献   

Basic fibroblast growth factor alleviates brain injury following global ischemia reperfusion in rabbits   总被引：9，自引：0，他引：9  

Zhang M  Ma YF  Gan JX  Jiang GY  Xu SX  Tao XL  Hong A  Li JK 《Journal of Zhejiang University. Science. B》2005,6(7):637-643

The aim of this study was to explore the protective effect of basic fibroblast growth factor (bFGF) on brain injury following global ischemia reperfusion and its mechanisms. Brain injury following global ischemia was induced by four vessels occlusion and systemic hypotension. Twenty-four rabbits were randomized into three groups: group A, only dissection of vessels; group B, intravenous infusion of normal saline after reperfusion for 6 h; group C, 30 μg/kg bFGF injected intravenously at the onset of reperfusion, then infused with 10 μg/(kg·h) for 6 h. Serum neuron specific enolase (NSE), S-100B, tumor necrosis factor-α(TNF-α), interleukin-1 (IL-1), interleukin-8 (IL-8) were measured before ischemia, 30 min after ischemia, 0.5, 1, 3, 6 h after reperfusion. Brain water content was determined and cerebral histopathological damages were compared. NSE and S-100B were increased 1 h after reperfusion and reached their peaks 6 h after reperfusion, but were much higher in group B than those in group C 3, 6 h after reperfusion. In groups B and C, TNF-a was increased after ischemia and IL-1 and IL-8 were increased significantly 0.5 h after reperfusion, then reached their peaks 6 h, 3 h, 6 h after reperfusion respectively. TNF-a and IL-8 at the time points of 1 h and 3 h and IL-1 at 3 h and 6 h in group C were correspondingly lower than those in group B. These indices in group A were nearly unchanged. There were less severe cerebral histopathological damages in group C compared with group B, but no difference in brain water content. It could be concluded that bFGF alleviates brain injury following global ischemia and reperfusion by down-regulating expression of inflammatory factors and inhibiting their activities.  相似文献   

试论高校图书馆与大学生信息素质教育     

马兰菊 《新疆教育学院学报》2007,23(3):145-147

信息素质是大学生整体素质的重要组成部分。本文从高校图书馆对大学生信息素质教育的优势为出发点,对信息素质教育的内容方式和途径等方面进行了论述。  相似文献   

转型背景下电气自动化专业人才培养模式研究     

王峥  刘黎明  马艳彬 《佳木斯教育学院学报》2016,(4):234-235

依托校企在人才培养、技术开发等领域的合作,与企业共建校内实训平台和校外实习基地。以职业能力培养为主线,以毕业生就业市场需求为导向,以服务商丘经济社会发展为宗旨,推进教学改革和人才培养模式改革,构建具有区域特色的人才培养体系和技术创新体系。  相似文献   

学区教研活动:问题与对策     

马连奇 《基础教育研究》2007,(4):22-24

近年来,为了弥补大范围活动的不便,出现了一种新的校际科研层次:学区教研组。由此形成了县教研室——学区教研组——校教研组的三级联动教研体系。县教育局根据学校的地域位置、教育发展状况、经济文化基础,同时考虑到优质资源的辐  相似文献   

初中美术教学方法多样化探析     

蒋萌  马宽斌 《桂林师范高等专科学校学报》2007,21(4):118-122

在初中美术教学中.可以从美术的画材、教学形式的转换、情感因素的利用等方面进行多样化的教学实践,以充分唤起学生的学习兴趣,尽可能地提高教学效果,从而实现美术课素质教育的目的。  相似文献   

探索区域性联合教学新模式   总被引：2，自引：0，他引：2  

马学为 《海军院校教育》2003,(1)

开放办学 ,联合培养人才是现代高等教育发展的必然趋势 ,它顺应了科学技术发展对教育改革的客观要求 ,也是推进军队院校现代化教学 ,提高人才培养质量的必由之路。加强区域联合教学 ,应充分发挥协作中心的作用 ,强化协调职能、健全协作机制 ,从军事斗争准备对高素质军事人才培养需要的高度 ,创建具有我军特色的区域性联合教学体系  相似文献   

论美国社会正义取向的教师教育     

马永全  陈思颖 《比较教育研究》2017,39(4)

美国教师教育具有关注社会正义的传统,其核心是认为教师教育的本质是政治的、学校再生产了社会不平等、课程体现着统治阶层的政治和文化霸权.基于社会重建理论和批判理论,社会正义取向教师教育的倡导者将教师教育作为实现社会正义的主要路径:重建教师教育的公共领域职能,将社会学理论引入教师教育,关注语言和文本分析.社会正义取向教师教育对当前美国教师教育产生了重要影响,不但拓展了教师教育研究的视野,也促使大学在教师教育实践中不断关注与种族和权力有关的社会正义问题.  相似文献